Molecular Formula | C13H4Cl2F6N4O4 |
Molar Mass | 465.09 |
Density | 1.766±0.06 g/cm3(Predicted) |
Boling Point | 380.5±42.0 °C(Predicted) |
pKa | -1.76±0.10(Predicted) |
In vitro study | Quantitative structure-activity relationships (QSAR) analyses of fungicidal activity of Fluazinam impurity 1 against Sphaerotheca fuliginea , Pyricularia oryzae and Rhizoctonia solani are carried out and the results are compared. In the case of S. fuliginea , a usual QSAR equation with Hammett's electronic parameter (sigma-m) and hydrophobicity (pi) is obtained, suggesting that the uncoupling mechanism might be involved in the mode of action. In the cases of P. oryzae and R. solani , QSAR equations are consisted of sigma-m, pi and the activity rank against Botrytis cinerea as independent variables,indicating both of uncoupling and SH-inhibition are working in the action mechanism. |
biological activity | Fluazinam impure 1 is a Fluazinam impurity with antifungal activity. Fluazinam opacity 1 is active against Sphaerotheca fuliginea,Pyricularia orizae and rhezoctonia solani. |
Target | Fungal |